Telehealth is regulated by the patient's location. A provider licensed in Florida cannot treat a patient sitting in Ohio without Ohio licensure, regardless of where the company is incorporated.
For a national brand this means maintaining a provider network with coverage in every state you sell into, and assigning cases by patient state rather than by availability.
Licensure is a standing operation rather than a one-time task: credentials expire, renew and lapse, and coverage gaps appear as decline rates in specific states.
Practising without licensure in the patient's state is a serious regulatory exposure. It is also an operational constraint that shapes which states you can profitably advertise in.
State licensure, in practice
Only in states where you intend to accept patients. PharmaBro maintains a credentialed provider network across all 50 states and D.C., so state coverage is not a constraint you have to solve yourself.